{"id":36,"date":"2021-05-20T07:56:45","date_gmt":"2021-05-20T06:56:45","guid":{"rendered":"http:\/\/sl-egis2.med.uni-jena.de\/index.php\/2021\/05\/20\/the-covid-19-puzzle-deciphering-pathophysiology-and-phenotypes-of-a-new-disease-entity\/"},"modified":"2024-05-30T11:43:09","modified_gmt":"2024-05-30T10:43:09","slug":"the-covid-19-puzzle-deciphering-pathophysiology-and-phenotypes-of-a-new-disease-entity","status":"publish","type":"post","link":"http:\/\/www.egis-online.eu\/index.php\/2021\/05\/20\/the-covid-19-puzzle-deciphering-pathophysiology-and-phenotypes-of-a-new-disease-entity\/","title":{"rendered":"The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity"},"content":{"rendered":"<p>Whereas the epidemiology of COVID-19 has dominated the news for months, knowledge of the pathophysiology of the disease remained largely in the background, despite the apparent clinical intricacies of multiple COVID-19 phenotypes.<\/p>\n<p>In a recent review published in Lancet Respiratory Medicine, the European Group on Immunology of Sepsis (EGIS) critically summarizes the most important findings of COVID-19 disease triggered by SARS-CoV-2&#8230;<\/p>\n<p>Whereas the epidemiology of COVID-19 has dominated the news for months, knowledge of the pathophysiology of the disease remained largely in the background, despite the apparent clinical intricacies of multiple COVID-19 phenotypes.<\/p>\n<p>In a recent review published in Lancet Respiratory Medicine, the European Group on Immunology of Sepsis (EGIS) critically summarizes the most important findings of COVID-19 disease triggered by SARS-CoV-2. The group of authors considers COVID-19 to be a novel viral disease entity with a pronounced vascular inflammatory component, characterized by a dysregulated immune response to the viral infection in severe courses.<\/p>\n<p>Osuchowski MF et al.: <a href=\"https:\/\/www.thelancet.com\/journals\/lanres\/article\/PIIS2213-2600(21)00218-6\/fulltext\">The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity<\/a>. Lancet Respir Med 2021 May 6 DOI: 10.1016\/S2213-2600(21)00218-6<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Whereas the epidemiology of COVID-19 has dominated the news for months, knowledge of the pathophysiology of the disease remained largely in the background, despite the apparent clinical intricacies of multiple COVID-19 phenotypes.<\/p>\n<p>In a recent review published in Lancet Respiratory Medicine, the European Group on Immunology of Sepsis (EGIS) critically summarizes the most important findings of COVID-19 disease triggered by SARS-CoV-2&#8230;<\/p>\n","protected":false},"author":1,"featured_media":35,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[62,64],"tags":[34,18,39,17,21],"class_list":["post-36","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-literature","category-publications","tag-covid-19","tag-literature","tag-pathophysiology","tag-publications","tag-recommendedreading"],"_links":{"self":[{"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/posts\/36","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/comments?post=36"}],"version-history":[{"count":1,"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/posts\/36\/revisions"}],"predecessor-version":[{"id":268,"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/posts\/36\/revisions\/268"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/media\/35"}],"wp:attachment":[{"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/media?parent=36"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/categories?post=36"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/tags?post=36"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}