{"id":468,"date":"2025-09-30T15:50:11","date_gmt":"2025-09-30T14:50:11","guid":{"rendered":"http:\/\/www.egis-online.eu\/?p=468"},"modified":"2025-10-27T15:51:48","modified_gmt":"2025-10-27T14:51:48","slug":"the-immunology-of-sepsis-translating-new-insights-into-clinical-practice","status":"publish","type":"post","link":"http:\/\/www.egis-online.eu\/index.php\/2025\/09\/30\/the-immunology-of-sepsis-translating-new-insights-into-clinical-practice\/","title":{"rendered":"The immunology of sepsis: translating new insights into clinical practice"},"content":{"rendered":"\n<p>In a recent review in <em>Nature Reviews Nephrology<\/em>, Matthijs Kox and a team of international collaborators discuss the state-of-the-art regarding the dysregulated host response in sepsis and conceptual frameworks that help understand this complex response. They advocate for a precision medicine approach, utilizing enrichment strategies, phenotyping, and smarter and flexible trial designs to identify effective immunomodulatory treatment strategies. <\/p>\n\n\n\n<p>Kox M et al. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40993251\/\">The immunology of sepsis: translating new insights into clinical practice.<\/a><em>Nat Rev Nephrol.<\/em> 2025 Sep 24. doi: 10.1038\/s41581-025-01004-6.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In a recent review in Nature Reviews Nephrology, Matthijs Kox and a team of international collaborators discuss the state-of-the-art regarding the dysregulated host response in sepsis and conceptual frameworks that help understand this complex response. They advocate for a precision medicine approach, utilizing enrichment strategies, phenotyping, and smarter and flexible trial designs to identify effective [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[62,64],"tags":[18,17,21],"class_list":["post-468","post","type-post","status-publish","format-standard","hentry","category-literature","category-publications","tag-literature","tag-publications","tag-recommendedreading"],"_links":{"self":[{"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/posts\/468","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/comments?post=468"}],"version-history":[{"count":1,"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/posts\/468\/revisions"}],"predecessor-version":[{"id":469,"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/posts\/468\/revisions\/469"}],"wp:attachment":[{"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/media?parent=468"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/categories?post=468"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.egis-online.eu\/index.php\/wp-json\/wp\/v2\/tags?post=468"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}