Kyriazopoulou E et al. Macrophage activation-like syndrome: an immunological entity associated with rapid progression to death in sepsis (2017) BMC Medicine 15: 172
This study by the Hellenic Sepsis Study Group investigated the frequency of macrophage activation-like syndrome (MALS) and explored biomarkers of diagnosis and prognosis.
Results show that MALS is an independent life-threatening entity in sepsis. Ferritin measurements can provide early diagnosis of MALS and may allow for specific treatment.