The article reports on the diagnostic performance of a molecular test (SeptiCyte LAB) to distinguish between sepsis and systemic inflammation of noninfectious etiology in critically ill adults.
The long-term consequences of sepsis on the immune system are currently only scarcely understood. Aiming to promote research on this critical gap, EGIS member Dr. Florian Uhle, together with the journal “Frontiers in Immunology” initiated the research topic “Long-term Consequences of Sepsis and Severe Trauma on Innate and Adaptive Immunity”.
The topic accepts manuscript submission until 16th February 2020. Vladimir Badovinac (Iowa City, USA) and Thomas Griffith (St. Paul, USA), both eminent researcher from the field, serve as further guest editors.
This paper by Kalayci et al. describes an interesting, new, and freely accessible web-based tool for the identification of human genes/proteins involved in disease-associated immune regulation. This might be useful also to research on the immunology of sepsis.
World Sepsis Day is held on September 13th every year and is an opportunity for people worldwide to unite in the fight against sepsis. Sepsis accounts for at least 7 to 9 million deaths worldwide annually. Yet, depending on country and education, sepsis is known only to 7 – 50 % of the people. Likewise, it is poorly known that sepsis can be prevented by vaccination and clean care and that early recognition and treatment drastically reduces sepsis mortality. This lack of knowledge makes sepsis the number one preventable cause of death worldwide.