Validation of a Host Response Assay for Discriminating Sepsis from SIRS

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The article reports on the diagnostic performance of a molecular test (SeptiCyte LAB) to distinguish between sepsis and systemic inflammation of noninfectious etiology in critically ill adults.

Miller RR, 3rd, Lopansri BK, Burke JP, Levy M, Opal S, Rothman RE, D’Alessio FR, Sidhaye VK, Aggarwal NR, Balk R, Greenberg JA, Yoder M, Patel G, Gilbert E, Afshar M, Parada JP, Martin GS, Esper AM, Kempker JA, Narasimhan M, Tsegaye A, Hahn S, Mayo P, van der Poll T, Schultz MJ, Scicluna BP, Klein Klouwenberg P, Rapisarda A, Seldon TA, McHugh LC, Yager TD, Cermelli S, Sampson D, Rothwell V, Newman R, Bhide S, Fox BA, Kirk JT, Navalkar K, Davis RF, Brandon RA, Brandon RB (2018) Validation of a Host Response Assay, SeptiCyte LAB, for Discriminating Sepsis from Systemic Inflammatory Response Syndrome in the ICU. Am J Respir Crit Care Med 198: 903-913

www.ncbi.nlm.nih.gov/pubmed/29624409

 

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European Group on Immunology of Sepsis

We are a multidisciplinary group consisting of basic scientists, immunologists, infectious diseases and intensive care medicine specialists with a shared primary research interest in sepsis immunology. Our overarching goal is to develop and foster collaborative research by working in partnership with groups with similar interests, Medical and Scientific Societies, Academia and the Industry. 

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