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Homeopathy for sepsis treatment
Continue reading →: Homeopathy for sepsis treatmentBavarian regional parlament has most recently voted for a large, long controversially debated homeopathy study for sepsis treatment, see link below (in German!). Seems like clinical sepsis research will not stagnate any longer…. and rather move backwards. I. Rubio ZEIT ONLINE: Bayerischer Landtag stimmt für umstrittene Homöopathie-Studie (7. Nov 2019)
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Current gaps in sepsis immunology: new opportunities for translational research
Continue reading →: Current gaps in sepsis immunology: new opportunities for translational researchIncreasing evidence supports a central role of the immune system in sepsis, but the current view of how sepsis affects immunity, and vice versa, is still rudimentary. The European Group on Immunology of Sepsis has identified major gaps that should be addressed with high priority, such as understanding how immunological…
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MOOC Innate Immunity – A new free online course of the Institut Pasteur
Continue reading →: MOOC Innate Immunity – A new free online course of the Institut PasteurThis MOOC is aimed to offer the most up-dated information on the cellular and molecular players of innate immunity, and on the mechanisms that lead to the elimination of the pathogens, of either bacterial, viral, fungal or parasitic origin. Accordingly, strategies of the pathogens against the innate immune system are…
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Validation of a Host Response Assay for Discriminating Sepsis from SIRS
Continue reading →: Validation of a Host Response Assay for Discriminating Sepsis from SIRSThe article reports on the diagnostic performance of a molecular test (SeptiCyte LAB) to distinguish between sepsis and systemic inflammation of noninfectious etiology in critically ill adults. Miller RR, 3rd, Lopansri BK, Burke JP, Levy M, Opal S, Rothman RE, D’Alessio FR, Sidhaye VK, Aggarwal NR, Balk R, Greenberg JA,…
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Call for participation – Frontiers in Immunology
Continue reading →: Call for participation – Frontiers in ImmunologyThe long-term consequences of sepsis on the immune system are currently only scarcely understood. Aiming to promote research on this critical gap, EGIS member Dr. Florian Uhle, together with the journal “Frontiers in Immunology” initiated the research topic “Long-term Consequences of Sepsis and Severe Trauma on Innate and Adaptive Immunity”.…
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ImmuneRegulation: a web-based tool for identifying human immune regulatory elements
Continue reading →: ImmuneRegulation: a web-based tool for identifying human immune regulatory elementsThis paper by Kalayci et al. describes an interesting, new, and freely accessible web-based tool for the identification of human genes/proteins involved in disease-associated immune regulation. This might be useful also to research on the immunology of sepsis. Kalayci S, Selvan ME, Ramos I, Cotsapas C, Harris E, Kim E-Y,…
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Sepsis Update 2019
Continue reading →: Sepsis Update 2019The 9th international congress “Sepsis & Multiorgan Dysfunction” will take place from 11 – 13 September 2019 in Weimar. As a part of the programme, the EGIS will hold a workshop on 11 September 2019. We are looking forward to seeing you there!
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Characterizing the immunophenotypes of lymphopenic community-acquired pneumonia
Continue reading →: Characterizing the immunophenotypes of lymphopenic community-acquired pneumoniaCommunity-acquired pneumonia (CAP) is the leading cause of sepsis. Whereas the host response has been analyzed regarding innate immunity and inflammatory response, adaptive immunity remained largely unexplored. Méndez et al. aimed to contribute to detailed immunoprofiling in CAP by evaluating the host’s adaptive immunity.
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Macrophage activation-like syndrome in sepsis
Continue reading →: Macrophage activation-like syndrome in sepsisKyriazopoulou E et al. Macrophage activation-like syndrome: an immunological entity associated with rapid progression to death in sepsis (2017) BMC Medicine 15: 172 This study by the Hellenic Sepsis Study Group investigated the frequency of macrophage activation-like syndrome (MALS) and explored biomarkers of diagnosis and prognosis. Results show that MALS…
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XII Valladolid Meeting on Sepsis 2019
Continue reading →: XII Valladolid Meeting on Sepsis 2019A multidisciplinary team of experts in Sepsis, including amongst others anaesthesiologists, immunologists, microbiologists and intensive care specialists, convened at this meeting, held in Valladolid in February 2019. Many interesting talks and engaging discussions covered the topics of sepsis definitions, therapeutic strategies, antibiotics, immunology of sepsis, and critical care of septic…
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