Coordinators
Members
- Almansa, Raquel
- Bauer, Michael
- Bouma, Hjalmar
- Brunkhorst, Frank M.
- Cajander, Sara
- Cavaillon, Jean-Marc
- Chousterman, Benjamin
- Deinhardt-Emmer, Stefanie
- Ferrer, Ricard
- Flohé, Stefanie B.
- García-Salido, Alberto
- Giamarellos-Bourboulis, Evangelos J.
- Kox, Matthijs
- Lachmann, Gunnar
- Martín-Loeches, Ignacio
- Monneret, Guillaume
- Nierhaus, Axel
- Osuchowski, Marcin
- Schefold, Joerg C.
- Scicluna, Brendon P.
- Shankar-Hari, Manu
- Skirecki, Tomasz
- Tampe, Björn
- Torres, Antoni
- Uhle, Florian
- Van der Poll, Tom
- Venet, Fabienne
- Weigand, Markus
- Weis, Sebastian
- Wiersinga, W. Joot
- Winkler, Martin S.
Jesús F Bermejo Martín, MD PhDHe leads a translational research group working at the National Health System in Valladolid, Spain, devoted to understand sepsis physiopathology and to identify biomarkers to predict, early detect and improve clinical management of this disease. The group accounts with regular financial support from the "Instituto de Salud Carlos III", and "Castilla y León Health Council", Spain, and collaborates with top international biotech companies such as Thermo Fisher or Inflammatix. Focus of research: in addition to biomarker discovery, the main interest of the group is studying the interaction between the immune system and the vascular endothelium in patients with chronic diseases as predisposing / triggering factor for Sepsis. He is one of the EGIS management coordinators. |
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Prof. Dr. Ignacio RubioBiochemist by training, he leads the experimental unit for sepsis research at the Clinic for Anesthesiology and Intensive Care of the University Hospital in Jena, Germany. His major research focus is the role of T-cells and monocytes in the course of the host response to sepsis. He is the second EGIS management coordinator. |
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Raquel Almansa, PhDRaquel Almansa is post-doctoral researcher working in the Biosepsis group at the National Health System in Spain. She is also associate professor of Genetics and Cell Biology at the School of Medicine, University of Valladolid. Raquel's research interest is focused in understanding host's immune response to infection, the interaction between the immune system and the vascular endothelium and to identify host biomarkers to predict, detect and improve management of infectious diseases at pre-hospital and hospital setting. |
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Prof. Dr. Michael BauerMichael Bauer is professor and chair for Anesthesiology and Critical Care Medicine as well as spokesman of the Integrated Research and Treatment Center for Sepsis Control and Care (CSCC) at Jena University Hospital. Research interests in sepsis are
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Hjalmar Bouma, MD, PhD, EuCPHjalmar Bouma is a physician-researcher and assistant professor trained as internist-acute medicine, experimental and clinical pharmacologist and immunologist, working at the University Medical Center Groningen, the Netherlands. He aims to improve early recognition of sepsis and develop personalized medicine, using a translational approach. Clinical data and biomaterials from up to 4,000 acutely ill patients per year are collected under his supervision by the Acutelines data-biobank to facilitate identification of (risk) markers predictive of response to therapy, which are further explored in pre-clinical models to identify novel therapeutic targets. His research group consists of both clinicians, as well as researchers with a background in data sciences and life sciences. More information: https://umcgresearch.org/w/early-sepsis. |
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Prof. Dr. Frank M. Brunkhorst, MDDirector of the Center for Clinical Studies and Full Professor for clinical sepsis research at the Jena University Hospital. Research fields:
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Sara Cajander, MD, PhD, Adjunct Assoc. Prof.Clinician-Scientist specialized in Infectious Diseases, Senior Consultant Physician at the Department of Infectious Diseases, Örebro University Hospital, and Adjunct Associate Professor at the Faculty of Medicine and Health, Örebro University, Sweden. |
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Prof. Dr. Jean-Marc CavaillonInterests:
Statement:
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Prof. Dr. Benjamin G. ChoustermanProf Benjamin G. Chousterman is a full professor of anesthesiology and critical care medicine at Université Paris Cité in Paris, France and the head of Lariboisière Surgical ICU. He holds a PhD in Immunology and leads a research team “Immuno-inflammation of the critically ill patients” that conducts a translational research program aiming at improving ICU patients outcome with the use of preclinical models, phenotyping studies and clinical trials with immunomodulatory drugs. |
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PD Dr. Stefanie Deinhardt-EmmerAs a senior physician specialized in microbiology, virology, and infection epidemiology, I lead a research group in the field of translational microbiology. My research primarily focuses on viral and bacterial lung infections, with a particular emphasis on understanding the impact of aging. I had the privilege of spending a postdoctoral year at the Buck Institute, CA, USA, working under the mentorship of Judy Campisi, a renowned expert in the field of aging and cellular senescence. I was honored with the Young Scientist Award from the German Society for Microbiology and Hygiene for my findings concerning pathomechanism of coinfections. Additionally, I was awarded the Animal Welfare Prize 2023 for my work in pioneering alternative methods, such as the ex vivo lung cut model. As a clinician scientist, I am a founding member of „ClinSciNet“- the german network of clinician scientists. |
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Ricard Ferrer MD, PhDDr. Ricard Ferrer is Head of the Intensive Care Department at Vall d’Hebron Hospital in Barcelona, Spain. He graduated in 1992 from the University of Barcelona, Medical School and pursued his specialisation in Intensive Care from 1994 to 1998 and his PhD title in 2010 from the Universitat Autonoma de Barcelona. |
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Prof. Dr. Stefanie B. Flohé, PhDMy main interest is the development of immunosuppression during sepsis and after severe injury in mice and men with emphasis on the function of dendritic cells and natural killer cells. I support EGIS since it represents a unique platform for scientific and clinical exchange that hopefully will boost the understanding of sepsis and the development of novel therapies. |
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Alberto García-Salido, MD, PhDAlberto García-Salido is specialist in pediatrics with expertise in Pediatric Intensive Care. Nowadays he carries out basic research at the Niño Jesús University Children's Hospital, Madrid. He has especial interest in the clinical application of flow cytometry in infectious diseases and inflammatory diseases with main focus on the innate immunity. Its investigations are developed in critical and not critical children focused in diagnosis, monitorization and to anticipate the clinical course. For further details: https://orcid.org/0000-0002-8038-7430 |
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Evangelos J. Giamarellos-Bourboulis, MD, PhD, Assoc. Prof.
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Matthijs Kox, PhD, Assoc. Prof.Matthijs Kox is assistant professor at the department of Intensive Care Medicine of the Radboud university medical centre in Nijmegen, the Netherlands. He supervises a team of 10 PhD candidates and a research technician, all of whom perform translational studies into modulation of the immune response, with a focus on sepsis. Furthermore, he pioneered studies into voluntary modulation of the sympathetic nervous system and immune response using a behavioral intervention developed by “Iceman” Wim Hof. For further details; please see: https://www.radboudumc.nl/en/people/matthijs-kox
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PD Dr. Gunnar Lachmann, MDClinician Scientist at the Department of Anesthesiology and Operative Intensive Care Medicine, Charité – Universitätsmedizin Berlin and coordinator of the HEMICU study, which investigates biomarkers for diagnosis of hemophagocytic lymphohistiocytosis (HLH) in critically ill patients. Research interests:
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Ignacio Martín-Loeches, MD PhDIgnacio Martin-Loeches, MD, PhD, EMBA (IESE), FJFICMI is a full time Consultant in Intensive Care Medicine, Senior Clinical Lecturer & Research Director of the Multidisciplinary Intensive Care Research Organization (MICRO) at Trinity College, Dublin. Currently Vice-Chair of Intensive Care Medicine at St James’s University Hospital, Dublin. He is the Chair of the Severe Sepsis and Septic Shock Working Group “4SWG”, Steering committee member for the Surviving Sepsis Campaign and Chair for CoBaTrICE at the ESICM. He is the currently member of the Clinical Trials of Health Research Board in Ireland. He is the Principal Investigator of European Regional Development Funds (ERDF) grants and the European Network for ICU-related respiratory infections (ENIRRIs) under the European Respiratory Society (ERS). He serves as section Editor at the Intensive Care Medicine (ICM) Journal. |
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Prof. Guillaume Monneret, MD PhDHe is Professor of Immunology and Head of Clinical Immunology Laboratory at Lyon University Hospitals (France). He leads a research group (EA7426, Claude Bernard University, Lyon, F) entitled “pathophysiology of injury-induced immunosuppression” - part of this group is a joint unit with bioMérieux dedicated to biomarkers from transcriptomic approach. Overall research focuses are: ICU-acquired immunosuppression (mechanisms, monitoring), immunotherapy in sepsis (e.g., IL-7) and standardized use of clinical flow cytometry. |
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Axel Nierhaus MD, EDICAxel Nierhaus is a senior consultant intensivist at the Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Germany. His department is one of the largest in the country, with 140 ICU beds and more than 8.500 adult patients per year. As a clinician-scientist, he is mainly interested in developing, testing and validating novel methods for real-life diagnosis of both innate and adaptive immune responses in patients with sepsis and septic shock. EGIS certainly is a unique platform for this. |
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Marcin Osuchowski, DVM PhDMarcin Osuchowski, DVM, PhD, is a head of Intensive Medicine at the Ludwig Boltzmann Institute for Experimental and Clinical Traumatology in Vienna, Austria. Dr. Osuchowski is a recipient of Fulbright fellowship (2000), the Best Young Investigator in Shock Research (2006) and Austrian Champion in European Research (2008). He is a coordinator for the Wiggers-Bernard Expert Consensus Initiative for Improvement of Animal Modeling in Sepsis (LBI Trauma/AUVA), co-coordinator (with DG Remick) of the Sepsis Model Scoring Taskforce (Shock Society) and currently serves as treasurer for the European Shock Society. Research interests:
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Prof. Joerg C. Schefold MD
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Brendon P. Scicluna, Ph.D.He is senior lecturer and principal investigator at the Department of Applied Biomedical Science, Faculty of Health Sciences, University of Malta, Malta. Brendon’s research focuses on the analysis of the immune response, innate immune memory, and host-pathogen interactions in pneumonia and sepsis. He is known to combine genomics, transcriptomics, epigenetics and immunology to define and understand host response archetypes in sepsis. |
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Manu Shankar-Hari, MSc PhDHe is clinician-scientist in Intensive Care Medicine, and group lead for a translational research group at King’s College London. Manu is currently funded by a prestigious UK NIHR Clinician Scientist Award. The research programme that he leads on includes:
For further details; please see: https://kclpure.kcl.ac.uk/portal/manu.shankar-hari.html |
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Tomasz Skirecki, MD PhDHead of the Laboratory of Flow Cytometry at Centre of Medical Postgraduate Education in Warsaw, Councillor of the European Shock Society, PI of the Polish National Science Center grants. Main research interest: role of immunity in organ dysfunction in sepsis, recovery of immune system after sepsis, animal models of sepsis
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PD Dr. Björn TampeBjörn Tampe is nephrologist, immunologist and intensive care practitioner and currently head of the intensive care medicine in the Department of Nephrology and Rheumatology at the University Medical Center Göttingen, Germany. Leading a translational research group, he is focusing on innate and adaptive immunity, particularly in the context of sepsis and autoimmune diseases. |
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Dr. Antoni Torres
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Dr. Florian UhleAs a biologist by training and translational medical scientist by passion, Dr. Uhle currently works as a research group leader at the Department of Anesthesiology of the Heidelberg University Hospital. His interdisciplinary team, consisting of biologists, physicians and bioinformaticians, strives to expand the mechanistic understanding of post-acute and long-term consequences of severe systemic inflammation on the host’s immune system. In this context, the group is also working on the identification and implementation of novel cellular and host-response biomarkers of infection and immunosuppression to inform clinical decision-making in the ICU. Acknowledging progress as a combined effort, he fully supports the unifying goal of EGIS to close current gaps in the knowledge about sepsis, ultimately aiming to improve therapy. |
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Prof. Tom Van der Poll, MD, PhDHe is Professor of Medicine and Chair of the Department of Medicine in the Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, the Netherlands. Van der Poll is board certified in Internal Medicine and Infectious Diseases. He is past Chair and current council member of the International Sepsis Forum. Van der Poll’s research focuses on pneumonia and sepsis, particularly on pathogenesis, the host response, immunotherapy and biomarkers. |
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Prof. Fabienne VenetProfessor of Immunology at Lyon-Est Medical School (Claude Bernard Lyon I University, Lyon, F), Fabienne Venet is leading a research team focused on the study of mechanisms leading to injury-acquired immunodeficiency within Prof G. Monneret’s research group “Pathophysiology of injury-induced immunosuppression” (EA7426, Claude Bernard University, Lyon, F).
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Prof. Dr. Markus WeigandProf. Markus Weigand is a board-certified anesthesiologist and head of the Department of Anesthesiology, Heidelberg University Hospital. He is currently chairman of the German Sepsis Society. He received extensive training on basic immunology during fellowships at world-renowned research institutions, including the German Cancer Research Center in Heidelberg and the Basel Institute of Immunology, which shaped his scientific profile and interest in translational immunology. His research focus now lies in the translation of basic research into the clinic, especially the application of precision therapy for the treatment of immune dysfunction in the context of nosocomial and opportunistic infections.
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Prof. Sebastian Weis, MDHe is Professor for Translational Infectious Disease, Senior Attending Physician at the Institute for Infectious Disease and Infection Control at the Jena University Hospital (Germany) and associated Principal Investigator Leibniz Institute for Natural Product Research and Infection Biology; Hans Knöll Institute (Leibniz-HKI). His research focusses on long term regulation of innate immunity and on mechanisms that preserve parenchymal functionality and integrity in sepsis, conferring metabolic adaptation and disease tolerance to infection. He is currently running the first human trial that aims at boosting disease tolerance mechanisms to improve the outcome of sepsis patients.
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Prof. W. Joot Wiersinga, MD, PhDHe is chair of the Division of Infectious Diseases of the Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands. He currently chairs the European Sepsis Academy and is on the executive committee of the ESCMID Study Group for Bloodstream Infections, Endocarditis and Sepsis – (ESGBIES) as well council member of the International Sepsis Forum (ISF). In addition he currently chairs the Infection group of the Surviving Sepsis Campaign guideline committee. Focus of research: Host-pathogen interactions and innate immune responses in infectious diseases Special interest in: sepsis, pneumonia, cellulitis, melioidosis, optimisation of antibiotic treatment and the gut microbiome. For further details; please see: www.amc.nl/wiersi |
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Martin Sebastian Winkler, MDMartin Winkler is currently working as a consultant at the Department of Anesthesiology and Intensive Care Medicine, University of Göttingen. Martin is interested in bench-to-bedside methods of immune monitoring in ICU and sepsis. Martin supports EGIS as an inspiring cross-border platform to create new ideas and methods.
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